| Fluor Marine Propulsion, LLC | 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) | $4.3B | $18.4B |
| Savannah River Nuclear Solutions LLC | 561210 Facilities Support Services | $3.4B | $12.0B |
| Advanced Technology International | 541714 Research and Development in Biotechnology (except Nanobiotechnology) | $419.4M | $4.6B |
| Central Plateau Cleanup Company, LLC | 562910 Remediation Services | $551.2M | $2.8B |
| Washington River Protection Solutions LLC | 562211 Hazardous Waste Treatment and Disposal | −$8.4M | $2.3B |
| Palmetto GBA, LLC | 524114 Direct Health and Medical Insurance Carriers | $296.1M | $1.6B |
| Fluor Intercontinental, Inc | 561210 Facilities Support Services | $287.2M | $925.9M |
| SO-PAK-Co, Inc | 311421 Fruit and Vegetable Canning | $175.1M | $915.8M |
| Detyens Shipyards Inc | 336611 Ship Building and Repairing | $270.0M | $865.0M |
| Companion Data Services LLC | 541512 Computer Systems Design Services | $171.7M | $719.7M |
| Elevated Technologies Services, LLC | 238290 Other Building Equipment Contractors | $310.8M | $538.5M |
| Southern Ohio Cleanup Company LLC | 562910 Remediation Services | $377.3M | $406.1M |
| Fluor Federal Services Inc | 541611 Administrative Management and General Management Consulting Services | −$6.3M | $389.8M |
| Atlas Technologies, Inc. | 541330 Engineering Services | $43.9M | $370.3M |
| US Foods Inc | 311812 Commercial Bakeries | $54.6M | $293.2M |
| South Carolina Commission for Blind | 722310 Food Service Contractors | $53.3M | $266.9M |
| Nuclear Waste Partnership LLC | 561210 Facilities Support Services | $0 | $257.9M |
| Hsgs-Ameresco, LLC | 236220 Commercial and Institutional Building Construction | $201.8M | $252.8M |
| Life Cycle Engineering Inc | 541330 Engineering Services | $18.6M | $236.7M |
| Orbis Sibro Inc | 541330 Engineering Services | $35.9M | $227.7M |
| FN America LLC | 332994 Small Arms, Ordnance, and Ordnance Accessories Manufacturing | $17.6M | $227.3M |
| Keenan FT Detrick Energy LLC | 221118 Other Electric Power Generation | $30.5M | $199.4M |
| Technica LLC | 561210 Facilities Support Services | $28.7M | $186.3M |
| VGS Infrastructure Services Inc | 561210 Facilities Support Services | $41.9M | $184.6M |
| Marinex Construction Inc | 237990 Other Heavy and Civil Engineering Construction | $6.9M | $184.4M |
| ITC Defense Corp | 541330 Engineering Services | $63.0M | $181.2M |
| Nexgen Data Systems Inc | 541330 Engineering Services | $7.3M | $179.7M |
| Adapt Forward LLC | 541330 Engineering Services | $13.7M | $154.0M |
| Mccall Farms Inc | 311421 Fruit and Vegetable Canning | $12.4M | $152.5M |
| Senn Bros., Inc. | 311991 Perishable Prepared Food Manufacturing | $3.5M | $152.4M |
| Savannah River Remediation LLC | 562211 Hazardous Waste Treatment and Disposal | $0 | $141.0M |
| Commit Enterprises Inc | 541330 Engineering Services | $38.2M | $134.7M |
| Westinghouse Government Services LLC | 334517 Irradiation Apparatus Manufacturing | $22.5M | $130.7M |
| Southeastern Paper Group, LLC | 322220 Paper Bag and Coated and Treated Paper Manufacturing | $18.4M | $112.4M |
| Mitchell Brothers Inc | 236220 Commercial and Institutional Building Construction | $1.2M | $111.8M |
| EOS Inc | 333618 Other Engine Equipment Manufacturing | $33.1M | $110.7M |
| Fluor Amec II, LLC | 561210 Facilities Support Services | $0 | $108.8M |
| VGS Aircraft Services, Inc. | 488119 Other Airport Operations | $22.5M | $98.4M |
| Jccbg | 236220 Commercial and Institutional Building Construction | $278K | $90.2M |
| Champion Aerospace LLC | 334416 Capacitor, Resistor, Coil, Transformer, and Other Inductor Manufacturing | $15.7M | $89.9M |
| MSI-Defence Systems US, LLC | 332994 Small Arms, Ordnance, and Ordnance Accessories Manufacturing | $4.1M | $89.4M |
| Precision Air Inc | 336413 Other Aircraft Parts and Auxiliary Equipment Manufacturing | $6.4M | $86.2M |
| Windward Enterprises, LLC | 333414 Heating Equipment (except Warm Air Furnaces) Manufacturing | $12.4M | $84.9M |
| Transox Inc | 532283 Home Health Equipment Rental | $21.4M | $84.7M |
| Alpha Genesis Inc | 112990 All Other Animal Production | $21.1M | $82.2M |
| modus21, LLC | 541330 Engineering Services | $26.6M | $76.2M |
| Titan Peach Farms Inc | 311411 Frozen Fruit, Juice, and Vegetable Manufacturing | $15.8M | $75.7M |
| Amentum Environment & Energy, Inc. | 562910 Remediation Services | $29.0M | $73.9M |
| University of South Carolina | 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) | $3.1M | $67.9M |
| Southern Dredging Co Inc | 237990 Other Heavy and Civil Engineering Construction | $4.8M | $66.9M |
| Boyer Commercial Construction Inc | 237110 Water and Sewer Line and Related Structures Construction | $19.4M | $65.5M |
| Palmetto Goodwill Services | 722310 Food Service Contractors | $9.0M | $63.9M |
| Seres Engineering & Services LLC | 561210 Facilities Support Services | $4.2M | $63.5M |
| BGI-ASI JV, LLC | 333310 Commercial and Service Industry Machinery Manufacturing | $8.5M | $60.5M |
| Metal Trades, LLC | 336611 Ship Building and Repairing | $1.3M | $60.3M |
| Chandler Construction Services, Inc. | 237110 Water and Sewer Line and Related Structures Construction | $16.5M | $60.1M |
| Brantley Construction Services, LLC | 236220 Commercial and Institutional Building Construction | $5.1M | $59.4M |
| Harbor Services, Inc | 236220 Commercial and Institutional Building Construction | $14.0M | $58.6M |
| Zigabyte Corporation | 541511 Custom Computer Programming Services | $13.1M | $58.5M |
| The Cameron Bell Corporation | 541330 Engineering Services | $3.8M | $57.8M |
| Pyramid Contracting LLC | 236220 Commercial and Institutional Building Construction | $5.0M | $55.6M |
| Liberty Business Associates, LLC | 541611 Administrative Management and General Management Consulting Services | $189K | $55.2M |
| Fathom 4 LLC | 541330 Engineering Services | $13.3M | $52.4M |
| Alphavets, Inc | 322291 Sanitary Paper Product Manufacturing | $18.3M | $52.3M |
| c2g, Ltd Co. | 488119 Other Airport Operations | $5.9M | $50.4M |
| Hightower Construction Co Inc | 236220 Commercial and Institutional Building Construction | $3.0M | $49.5M |
| Integer Technologies LLC | 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) | $14.7M | $49.2M |
| Usvetserv, LLC | 339113 Surgical Appliance and Supplies Manufacturing | $12.7M | $48.8M |
| NAR Medical Depot, LLC | 339112 Surgical and Medical Instrument Manufacturing | $8.4M | $48.8M |
| Corg Management Group LLC | 561210 Facilities Support Services | $3.0M | $48.6M |
| Istari Federal LLC | 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) | $2.9M | $46.4M |
| Phronesis Global Training Solutions LLC | 541512 Computer Systems Design Services | $9.1M | $46.2M |
| Dominion Energy South Carolina, Inc. | 221112 Fossil Fuel Electric Power Generation | $6.8M | $45.3M |
| R.S. Means Company LLC | 513210 Software Publishers | $5.9M | $44.7M |
| Seres-Arcadis SB jv2 LLC | 562910 Remediation Services | $3.5M | $44.4M |
| Premier Medical Distributors, LLC | 339113 Surgical Appliance and Supplies Manufacturing | $29.0M | $43.6M |
| Dean/Fluor, LLC | 561210 Facilities Support Services | $9.5M | $40.9M |
| Lockheed Martin Logistic Services, Inc. | 336413 Other Aircraft Parts and Auxiliary Equipment Manufacturing | $8.3M | $39.5M |
| Morgan 6, LLC | 541611 Administrative Management and General Management Consulting Services | $7.5M | $39.4M |
| Cems-RS&H JV | 541330 Engineering Services | $3.4M | $38.1M |
| Netrist Solutions, LLC | 541511 Custom Computer Programming Services | $0 | $37.6M |
| Seres-Arcadis SB JV, LLC | 562910 Remediation Services | $50K | $37.5M |
| County of Horry | 324110 Petroleum Refineries | $3.6M | $36.3M |
| L-J Inc | 237990 Other Heavy and Civil Engineering Construction | $70K | $34.8M |
| The Construction Services Group Inc | 236220 Commercial and Institutional Building Construction | −$791K | $34.4M |
| Catawba-TEA, LLC | 562910 Remediation Services | −$2.4M | $33.3M |
| TRU Simulation + Training Inc | 333318 Other Commercial and Service Industry Machinery Manufacturing | $0 | $33.2M |
| Alston Wilkes Society | 623990 Other Residential Care Facilities | $6.5M | $33.1M |
| Paula F Price Enterprises LLC | 325120 Industrial Gas Manufacturing | $7.9M | $31.3M |
| Medshore Ambulance Service, Inc. | 621910 Ambulance Services | $5.9M | $30.9M |
| RPI-CSS, LLC | 541620 Environmental Consulting Services | $14.9M | $30.0M |
| Cems Engineering Inc | 541330 Engineering Services | $4.9M | $30.0M |
| The Medical University of South Carolina | 541380 Testing Laboratories and Services | $6.1M | $29.8M |
| Medpro Systems LLC | 236220 Commercial and Institutional Building Construction | $10.8M | $29.7M |
| M-E jv2 LLC | 488190 Other Support Activities for Air Transportation | $10.4M | $29.1M |
| VSS Logistics LLC | 493110 General Warehousing and Storage | $4.4M | $29.0M |
| Community Pastor Care LLC | 485991 Special Needs Transportation | $1.3M | $28.9M |
| Carson Industries, Inc. | 333314 Optical Instrument and Lens Manufacturing | $4.0M | $28.2M |
| Allserv Inc | 561730 Landscaping Services | $7.9M | $27.8M |
| Cccs International LLC | 236220 Commercial and Institutional Building Construction | $792K | $27.5M |
| The Gordian Group, Inc. | 511210 Software Publishers | $7.6M | $26.8M |
| Sofx, Inc. | 315210 Cut and Sew Apparel Contractors | $5.0M | $26.7M |
| A. James Global Services, Inc | 561210 Facilities Support Services | $2.6M | $25.4M |
| Tacmed Simulation, Inc | 423450 Medical, Dental, and Hospital Equipment and Supplies Merchant Wholesalers | $1.5M | $24.8M |
| International Mortuary Shipping, LLC | 812210 Funeral Homes and Funeral Services | $5.3M | $24.2M |
| ADC Engineering Inc | 541330 Engineering Services | $38K | $24.0M |
| North American Rescue, LLC | 423450 Medical, Dental, and Hospital Equipment and Supplies Merchant Wholesalers | $3.9M | $23.8M |
| Research Planning, Inc. | 541620 Environmental Consulting Services | $9.6M | $23.5M |
| INK to Think LLC | 541611 Administrative Management and General Management Consulting Services | $10.0M | $23.5M |
| Iva'al/Nais Technologies LLC | 541519 Other Computer Related Services | $0 | $23.4M |
| Envirosmart, LLC | 561210 Facilities Support Services | $2.9M | $22.5M |
| V Pavkov Contracting Co Inc | 237990 Other Heavy and Civil Engineering Construction | $1.1M | $22.4M |
| nd3 Inc | 561210 Facilities Support Services | $6.8M | $22.0M |
| Sunbelt Rentals, Inc | 532310 General Rental Centers | $3.6M | $21.8M |
| sa3 Construction Management LLC | 541330 Engineering Services | $8.7M | $21.2M |
| Infotec Systems Corp | 541512 Computer Systems Design Services | $1.9M | $20.2M |
| Siris LLC | 541330 Engineering Services | $12.9M | $19.8M |
| q2 Administrators, LLC | 541611 Administrative Management and General Management Consulting Services | $5.2M | $18.2M |
| Catawba Teapec LLC | 562910 Remediation Services | $15.4M | $18.1M |
| Maccs-Easi JV 1 LLC | 488190 Other Support Activities for Air Transportation | $0 | $17.2M |
| The Citadel | 611310 Colleges, Universities, and Professional Schools | $4.8M | $17.0M |
| Jankel Tactical Systems LLC | 336992 Military Armored Vehicle, Tank, and Tank Component Manufacturing | $3.7M | $16.5M |
| Agfa US Corp | 423450 Medical, Dental, and Hospital Equipment and Supplies Merchant Wholesalers | $2.2M | $16.3M |
| Target Contractors LLC | 238910 Site Preparation Contractors | $234K | $16.2M |
| Cape Romain Contractors, Inc | 237990 Other Heavy and Civil Engineering Construction | $439K | $16.0M |
| Ashridge Inc | 237990 Other Heavy and Civil Engineering Construction | $0 | $15.0M |
| Form FIT & Function LLC | 336413 Other Aircraft Parts and Auxiliary Equipment Manufacturing | $312K | $14.7M |
| Seres-Arcadis 8(a) jv2 LLC | 562910 Remediation Services | −$744K | $14.7M |
| George Consulting Ltd | 541330 Engineering Services | $6.0M | $14.7M |
| Empire Aircraft Services Inc | 488119 Other Airport Operations | $2.5M | $14.0M |
| DFA Dairy Brands Fluid, LLC | 311812 Commercial Bakeries | $5.1M | $13.1M |
| Claene Group LLC | 561990 All Other Support Services | $2.6M | $13.0M |
| E-VAC Magnetics LLC | 332999 All Other Miscellaneous Fabricated Metal Product Manufacturing | $12.9M | $12.9M |
| TD Synnex Corporation | 334111 Electronic Computer Manufacturing | $221K | $12.7M |
| Columbia Aviation Corp | 324110 Petroleum Refineries | $0 | $12.4M |
| Acucyber LLC | 541330 Engineering Services | $6.1M | $12.4M |
| Dietary Equipment Incorporated | 333241 Food Product Machinery Manufacturing | $443K | $12.4M |
| Varnermiller LLC | 611310 Colleges, Universities, and Professional Schools | −$52K | $12.2M |
| Christie Brothers-SBG JV LLC | 236220 Commercial and Institutional Building Construction | $4.7M | $11.5M |
| Milliken & Company | 313210 Broadwoven Fabric Mills | $1.9M | $11.0M |
| Avenger Aerospace Solutions Inc | 488190 Other Support Activities for Air Transportation | $5.0M | $10.8M |
| Special Care Medical of South Carolina Inc | 532283 Home Health Equipment Rental | $0 | $10.8M |
| RAE Management Services LLC | 812320 Drycleaning and Laundry Services (except Coin-operated) | $371K | $10.6M |
| Altron, Inc. | 541713 Research and Development in Nanotechnology | $678K | $10.3M |
| Jordon Construction Company L.L.C | 238160 Roofing Contractors | $574K | $10.1M |
