Top NASA research and development in biotechnology (except nanobiotechnology) contractors
In the 12 months ending Oct 5, 2026, the National Aeronautics and Space Administration obligated $22.3M in net prime contract dollars under NAICS 541714, up 44.0% from $15.5M in the preceding 12 months. 7 prime contractors received positive obligations, and 3 of them accounted for 80% of that spend.
Prime contracts funded by the National Aeronautics and Space Administration. Latest 12 months: Oct 6, 2025 to Oct 5, 2026. Source: USAspending.gov.
Obligations by fiscal year
Net prime contract obligations by federal fiscal year (October to September).
Top NASA contractors for NAICS 541714
Ranked by positive obligations in the latest 12 months. Share is of all positive obligations in this market.
| # | Contractor | Latest 12 mo | Prior 12 mo | Share | Rank change |
|---|---|---|---|---|---|
| 1 | STI Legacy, Inc. | $11.8M | $6.4M | 52.7% | — |
| 2 | Aspera Biomedicines, Inc. | $4.3M | $2.2M | 19.2% | ▲ 2 |
| 3 | National Stem Cell Foundation Inc. | $2.8M | $900K | 12.4% | ▲ 2 |
| 4 | Redwire Space Technologies, Inc. | $2.2M | $2.5M | 9.7% | ▼ 1 |
| 5 | Sierra Space Corp | $1.2M | $3.2M | 5.5% | ▼ 3 |
| 6 | Melanie Sauer & Associates LLC | $55K | $55K | 0.3% | ▲ 1 |
| 7 | Openteams Inc | $25K | $0 | 0.1% | New |
What changed in the last 12 months
Contractors with the largest change in reported obligations versus the preceding 12 months.
Largest gains
- STI Legacy, Inc.$6.4M → $11.8M (+$5.3M) · now #1
- Aspera Biomedicines, Inc.$2.2M → $4.3M (+$2.1M) · now #2
- National Stem Cell Foundation Inc.$900K → $2.8M (+$1.9M) · now #3
Largest declines
- Sierra Space Corp$3.2M → $1.2M (−$2.0M) · now #5
- Redwire Space Technologies, Inc.$2.5M → $2.2M (−$330K) · now #4
- Orbital Mining Corporation$150K → $0 (−$150K) · no latest-period obligations
New to this market
1 contractors received their first obligations in this market (since FY2022) during the latest 12 months. The largest:
| Contractor | First obligation | Latest 12 mo |
|---|---|---|
| Openteams Inc | Jan 20, 2026 | $25K |
Where the money comes from
Funding sub-agencies within the National Aeronautics and Space Administration, latest 12 months. The funding organization can differ from the office that runs the requirement.
| Funding sub-agency | Latest 12 mo | Prior 12 mo | Change |
|---|---|---|---|
| National Aeronautics and Space Administration | $22.3M | $15.5M | Up $6.8M (44.0%) |
Potential recompetes
Large awards in this market whose current period of performance ends in the next 18 months. Treat these as research leads: options, extensions, and follow-on vehicles often change the timing.
| Award | Incumbent | Obligated | Current end |
|---|---|---|---|
| 80JSC026FA027 | STI Legacy, Inc. PREPARE A FEASIBILITY ASSESSMENT OF LONG-TERM DEEP SPACE AVATAR RESEARCH OPPORTUNITIES. THESE EXPERIMENTS WILL UTILIZE AUTONOMOUS SYSTEMS ENABLING LONGER TERM SCIENCE OPERATIONS… | $3.4M | Oct 30, 2026 |
| 80JSC024FA073 | STI Legacy, Inc. A VIRTUAL ASTRONAUT TISSUE ANALOG RESPONSE (AVATAR) MISSIONS | $10.2M | Dec 31, 2026 |
| 80JSC023FA162 | STI Legacy, Inc. FOUR FULL SERVICE PAYLOAD INTERGRATION USES | $1.8M | Dec 31, 2026 |
| 80JSC025PA002 | National Stem Cell Foundation Inc. DESIGN, DEVELOPMENT, AND TESTING OF GROUND AND FLIGHT UNIT(S) AS WELL AS COMPLETION OF FLIGHT DEMONSTRATION(S) ON THE ISS NATIONAL LAB (NL) OR A CLD OR OTHER LEO ORBITAL PLATFORM. | $3.7M | Sep 30, 2027 |
| 80JSC026FA127 | STI Legacy, Inc. FEASIBILITY STUDY OF FLYING ORGANOIDS IN LEO USING THE SAME PAYLOAD MODEL AS FLOWN ON ARTEMIS II. | $2.8M | Dec 30, 2027 |
| 80JSC025PA001 | Aspera Biomedicines, Inc. RESEARCH AND DEVELOPMENT FOR IN-SPACE PRODUCTION CONCEPTS OF NANOBIOREACTOR MODELS. THIS WAS AWARDED OFF OF THE NASA RESEARCH ANNOUNCEMENT NNJ13ZBG001N. NOTE THAT "BASIC… | $6.5M | Feb 15, 2028 |
Common questions
Who are the top NASA contractors for NAICS 541714?
In the latest 12 months, STI Legacy, Inc. ($11.8M), Aspera Biomedicines, Inc. ($4.3M), National Stem Cell Foundation Inc. ($2.8M) received the most NASA obligations for research and development in biotechnology (except nanobiotechnology).
How concentrated is this market?
The eight largest primes held 100.0% of positive obligations, and STI Legacy, Inc. alone held 52.7%. 1 contractors won their first obligations in this market during the latest 12 months.
Are any large NASA NAICS 541714 contracts ending soon?
6 of the largest awards in this market reach their current end date in the next 18 months. The first is 80JSC026FA027 (STI Legacy, Inc., $3.4M obligated), ending Oct 30, 2026. An end date is a research lead, not a confirmed recompete: options and extensions often move it.
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$33.5MFigures are net obligations on prime contracts (award types A–D) from USAspending.gov, grouped by funding agency and the NAICS code on each award. Net obligations include deobligations and corrections, so they can differ from positive-obligation totals. See methodology.
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