Top HHS research and development in the physical, engineering, and life sciences (except biotechnology) contractors
In the 12 months ending Oct 5, 2026, the Department of Health and Human Services obligated $30.6M in net prime contract dollars under NAICS 541712, up 145.2% from $12.5M in the preceding 12 months. 12 prime contractors received positive obligations, and 3 of them accounted for 80% of that spend.
Prime contracts funded by the Department of Health and Human Services. Latest 12 months: Oct 6, 2025 to Oct 5, 2026. Source: USAspending.gov.
Obligations by fiscal year
Net prime contract obligations by federal fiscal year (October to September).
Top HHS contractors for NAICS 541712
Ranked by positive obligations in the latest 12 months. Share is of all positive obligations in this market.
| # | Contractor | Latest 12 mo | Prior 12 mo | Share | Rank change |
|---|---|---|---|---|---|
| 1 | Social & Scientific Systems, Inc. | $19.5M | $13.7M | 45.6% | — |
| 2 | Astrix Technology LLC | $10.7M | $13.5M | 25.1% | — |
| 3 | Research Triangle Institute | $5.3M | $5.0M | 12.5% | ▲ 1 |
| 4 | Mriglobal | $3.3M | $3.1M | 7.7% | ▲ 1 |
| 5 | PPD Development LP | $2.0M | −$19.1M | 4.7% | New |
| 6 | Lovelace Biomedical Research Institute | $1.3M | $1.7M | 3.0% | ▲ 4 |
| 7 | Integrated Laboratory Systems, LLC | $360K | $5.0M | 0.8% | ▼ 4 |
| 8 | ICF Incorporated, L.L.C. | $160K | $1.8M | 0.4% | ▲ 1 |
| 9 | Advanced Bioscience Laboratories, Inc. | $21K | −$2.6M | 0.1% | New |
| 10 | Oregon Health & Science University | $9K | $8K | 0.0% | ▲ 8 |
| 11 | University of California, Davis | $9K | $36K | 0.0% | ▲ 4 |
| 12 | The Trustees of Columbia University in the City of New York | $5K | −$281 | 0.0% | New |
What changed in the last 12 months
Contractors with the largest change in reported obligations versus the preceding 12 months.
Largest gains
- PPD Development LP−$19.1M → $2.0M (+$21.1M) · now #5
- Social & Scientific Systems, Inc.$13.7M → $19.5M (+$5.8M) · now #1
- American Type Culture Collection−$3.3M → $0 (+$3.3M) · no latest-period obligations
Largest declines
- Integrated Laboratory Systems, LLC$5.0M → $360K (−$4.7M) · now #7
- Burleson Research Technologies, Inc.$301K → −$2.7M (−$3.0M) · no latest-period obligations
- Thomas Jefferson University$2.7M → −$91K (−$2.8M) · no latest-period obligations
Where the money comes from
Funding sub-agencies within the Department of Health and Human Services, latest 12 months. The funding organization can differ from the office that runs the requirement.
| Funding sub-agency | Latest 12 mo | Prior 12 mo | Change |
|---|---|---|---|
| National Institutes of Health | $31.0M | $17.4M | Up $13.6M (78.2%) |
Potential recompetes
Large awards in this market whose current period of performance ends in the next 18 months. Treat these as research leads: options, extensions, and follow-on vehicles often change the timing.
| Award | Incumbent | Obligated | Current end |
|---|---|---|---|
| HHSN27500006 | University of Washington CCTN- MALE SITES - CONTRACEPTIVE EFFICACY CLINICAL TRIAL HHSN275201300025I/HHSN27500006 | $2.7M | Dec 31, 2026 |
| 75N96021F00002 | Social & Scientific Systems, Inc. CONTRACTOR: SOCIAL & SCIENTIFIC SYSTEMS, INC. TASK ORDER: 75N96021F00002 - RESEARCH DEVELOPMENT BASE PERIOD: JUNE 30, 2021 - JUNE 29, 2022 CAN 8469992 | $3.4M | Dec 31, 2026 |
| HHSN273201400020C | Mriglobal CHEMISTRY SERVICES FOR THE NTP | $20.4M | Jan 17, 2027 |
| HHSN273201400027C | Battelle Memorial Institute CHEMISTRY SERVICES FOR THE NTP | $15.3M | Jan 24, 2027 |
| HHSN272201700082C | Thomas Jefferson University ADVANCED DEVELOPMENT OF MULTIVALENT VACCINE CANDIDATES FOR FILOVIRUS AND LASSA FEVER | $5.9M | Jan 31, 2027 |
| HHSN273201400022C | Research Triangle Institute CHEMISTRY SERVICES FOR THE NATIONAL TOXICOLOGY PROGRAM | $24.9M | Jan 31, 2027 |
| 75N92023F00070 | Astrix Technology LLC PROFESSIONAL SUPPORT SERVICES FOR THE NHLBI DIVISION OF INTRAMURAL RESEARCH (DIR) | $5.5M | Feb 28, 2027 |
| 75N95020F00001 | Lovelace Biomedical Research Institute NON-CLINICAL SAFETY ASSESSMENT OF GENE THERAPY (PCCA, MMAB, DOK7 AND COLQ) TO SUPPORT PLATFORM GENE THERAPY FOR CONGENITAL MYASTHENIC DISEASES (DOK7, COLQ) AND ACIDEMIA (PCCA,… | $3.0M | May 31, 2027 |
| 75N96026F00007 | Social & Scientific Systems, Inc. CLIN1: PROTOCOL DEVELOPMENT AND SCIENTIFIC RESEARCH; CLIN2: BIOSPECIMENS AND LABORATORY SCIENCE; CLIN3-EPIDEMIOLOGY, BIOSTATISTICS, AND STATISTICAL PROGRAMMING; SEVERABLE SERVICES | $5.5M | Jun 29, 2027 |
| 75N93021F00002 | Advanced Bioscience Laboratories, Inc. THIS TASK ORDER IS FOR (A) DOWNSTREAM ENGINEERING RUN PRODUCTION, (B) DOWNSTREAM CURRENT GOOD MANUFACTURING PRACTICES MANUFACTURING PRODUCTION (CGMP), (C) FILL/FINISH & LABELING,… | $2.5M | Jun 30, 2027 |
Common questions
Who are the top HHS contractors for NAICS 541712?
In the latest 12 months, Social & Scientific Systems, Inc. ($19.5M), Astrix Technology LLC ($10.7M), Research Triangle Institute ($5.3M) received the most HHS obligations for research and development in the physical, engineering, and life sciences (except biotechnology).
How concentrated is this market?
The eight largest primes held 99.9% of positive obligations, and Social & Scientific Systems, Inc. alone held 45.6%. 0 contractors won their first obligations in this market during the latest 12 months.
Are any large HHS NAICS 541712 contracts ending soon?
10 of the largest awards in this market reach their current end date in the next 18 months. The first is HHSN27500006 (University of Washington, $2.7M obligated), ending Dec 31, 2026. An end date is a research lead, not a confirmed recompete: options and extensions often move it.
Related markets
NAICS 541712 across all agencies
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$6.3MFigures are net obligations on prime contracts (award types A–D) from USAspending.gov, grouped by funding agency and the NAICS code on each award. Net obligations include deobligations and corrections, so they can differ from positive-obligation totals. See methodology.
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